The Spezzamonte brothers, founders of Estro, take their wine seriously—more than 500 bottles are available at this stylish modern enoteca. Wait staff will help you wade through the wine list, and you are free to drop in for just a glass or two, sample some cicchetti, stay for a full meal or purchase a bottle to go. Interiors were executed by Venetian craftspeople, as were glassware and lamps. The youthful, innovative energy here will make you feel like you’ve stumbled on a real “insiders” place—and you have.
Time Out tip: When you tire of Italian food during your vacation in Italy—unthinkable, but it does happen—Estro’s burgers win high marks.
Nearby:
Traghetto di San Tomà: For a quick trip across the canal, without having to hoof it to a bridge
Giardini Papadopoli: For a shady patch of terra firma in a watery city
Pasticceria Tonolo: For a gorgeously wrapped confection to take back home