The Duomo is one of Milan's most famous landmarks and tells a story of faith and art spanning over six centuries. The 14th-century cathedral is home to airy marble interiors and exquisite stained-glass windows and is 600 years in the making, reflecting the city's creativity and ambition. If you want to skip the long lines at the ticket office, buy your tickets online beforehand.
Time Out tip: Want a good photo op? A real focal point of the cathedral is its numerous spires, so it's well worth going up to the terrace.