South meets South of the Border at this Upper East Side canteen, the second iteration of the restaurant. At the 3,400-square-foot Manhattan location—outfitted with exposed-brick walls and leather banquettes—find menu staples like BBQ brisket tacos and baby back ribs with jalapeño-goat-cheese corn bread. Location exclusives include grilled rib-eye, salmon fillet and spice-rubbed beef ribs. Drinkers can choose from the 48-draft tap (Chelsea Blackberry Wheat, Dogfish Head Chicory Stout) and gussied-up margaritas (passion fruit–jalapeño, guava-chipotle).
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