1. Opera del Duomo
What is it: The museum of Cathedral of Saint Mary of the Flower, better known as Il Duomo di Firenze.
Why go: Just having undergone an impressive renovation, the museum of the Duomo is not to be missed, with its prized possession the recently restored “Doors of Paradise” that were originally on the Baptistery. This museum also has a three-story facade to show the Duomo as it was before the most recent facelift (in 1587). Also expect to find incredible masterpieces from the likes of Donatello, Michelangelo and more, including the latter’s The Pietà, which he started working on in his 70s and eventually attempted to destroy.